Figure 2
From: Resting hyperinflation and emphysema on the clinical course of COPD
The combined associations of resting hyperinflation and emphysema with acute exacerbation. (a) Time to first acute exacerbation. Footnotes: Group 1: RV/TLC ≤ upper limit of normal (ULN) and emphysema index ≤ 10%, Group 2: RV/TLC ≤ ULN and emphysema index >10%, group 3: RV/TLC > ULN and emphysema index ≤ 10%, group 4: RV/TLC > ULN and emphysema index >10%. All statistical analyses were adjusted by age, sex, body mass index, pack-years smoked, smoking status, SGRQ score (≥25 vs <25), exacerbation history (≥2 total or ≥1 severe exacerbations vs <2 total and 0 severe exacerbation) in the past year at baseline, and use of ICS/LABA or LAMA. *P-value < 0.05. (b) Incidence rate of acute exacerbation. Footnotes: Group 1: RV/TLC ≤ upper limit of normal (ULN) and emphysema index ≤ 10%, Group 2: RV/TLC ≤ ULN and emphysema index >10%, group 3: RV/TLC > ULN and emphysema index ≤ 10%, group 4: RV/TLC > ULN and emphysema index >10%. All statistical analyses were adjusted by age, sex, body mass index, pack-years smoked, smoking status, SGRQ score (≥25 vs <25), exacerbation history (≥2 total or ≥1 severe exacerbations vs <2 total and 0 severe exacerbation) in the past year at baseline, and use of ICS/LABA or LAMA. *P-value < 0.05.
