Table 2 Relationship between knee joint damage (Modified Mankin Score), rat metabolic profile and cecal microbiota.

From: Protective effect of prebiotic and exercise intervention on knee health in a rat model of diet-induced obesity

 

Knee Joint Damage

 

Knee Joint Damage

r

p-value

r

p-value

Percent body fat

0.327

0.014

Bacteroides/Prevotella

−0.328

0.013

SF: leptin

0.451

0.001

Bifidobacterium

−0.320

0.016

Serum: leptin

0.389

0.003

Enterobacteriaceae

0.210

0.121

Endotoxin

0.455

<0.001

Lactobacillus

−0.125

0.359

CISI

−0.327

0.010

C. coccoides (cluster XIV)

−0.020

0.885

Total cholesterol

0.343

0.012

C. leptum (cluster IV)

0.436

0.001

HDL-cholesterol

0.230

0.087

C. cluster I

0.226

0.094

LDL-cholesterol

0.264

0.052

C. cluster XI

0.206

0.127

Non-HDL cholesterol

0.399

0.015

Roseburia

−0.294

0.028

Triglycerides

0.546

<0.001

Methanobrevibacter

0.237

0.079

Ratio: Total Chol/HDL

0.220

0.116

Akkemansia muciniphila

0.307

0.021

Ratio: Trig/HDL

0.330

0.017

Faecalibacterium prausnitzii

0.457

<0.001

   

Collinsella aerofaciens

0.008

0.953

  1. r: Pearson’s correlation coefficient; SF: synovial fluid; CISI: composite insulin sensitivity index; HDL: high density lipoprotein; LDL: low density lipoprotein; Chol: cholesterol. Trig: triglycerides.
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