Figure 1

The CD spectra of the duplexes containing: (A) the G-C base pair in different sequential contexts (duplexes M9, M11, M13 and M15), (B) the s6G-C base pair in different sequential contexts (duplexes M10, M12, M14 and M16), (C) all the G-X base pairs/mismatches in a single sequential context (duplexes M9, M17, M19 and M21) and (D) all the s6G-X base pairs/mismatches in a single sequential context (duplexes M10, M18, M20 and M22). X is A, G or U.