Figure 3 | Scientific Reports

Figure 3

From: PKD1 Duplicated regions limit clinical Utility of Whole Exome Sequencing for Genetic Diagnosis of Autosomal Dominant Polycystic Kidney Disease

Figure 3

WES and Target enrichment coverage map of PKD1. WES of exons 1 to 32 of PKD1 showed low coverage while PKD2 coverage showed proper depth of all exons. Target Enrichment showed proper coverage for coding regions of PKD1 and PKD2. SureSelect v6 improved the coverage of PKD1 in comparison to WES TruSeq v3 but exons 1 to 14 remained poorly covered. WGS showed proper covering of the entire PKD1.

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