Table 1 Left: Allele frequencies of HLA-A antigens in the Japanese Behçet’s disease patient population.
From: The association analysis between HLA-A*26 and Behçet’s disease
HLA-A allele | BD cases (N = 611) | Controls (N = 2,955) | p | Pc | HLA-A*26 phenotype | BD cases (N = 611) | Controls (N = 2,955) | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
n | Allele freq. | n | Allele freq. | N | Phenotype freq. | N | Phenotype freq. | ||||
A*01 | 17 | 1.40% | 40 | 0.68% | 0.0108 | 0.1188 | A*26 positive | 214 | 35.55% | 601 | 20.68% |
A*02 | 267 | 22.07% | 1,380 | 23.60% | NS | A*26 negative | 388 | 64.45% | 2,305 | 79.32% | |
A*03 | 1 | 0.08% | 25 | 0.43% | NS | Total | 602 | 100.00% | 2,906 | 100.00% | |
A*11 | 75 | 6.20% | 543 | 9.29% | 0.0005 | 0.0055 | Undetermined | 9 | — | 49 | — |
A*24 | 434 | 35.87% | 2,225 | 38.05% | NS | ||||||
A*26 | 223 | 18.43% | 639 | 10.93% | <0.0001 | <0.0001 | |||||
A*30 | 0 | 0.00% | 15 | 0.26% | NS | ||||||
A*31 | 136 | 11.24% | 498 | 8.52% | 0.0026 | 0.0286 | |||||
A*32 | 0 | 0.00% | 2 | 0.03% | NS | ||||||
A*33 | 57 | 4.71% | 481 | 8.23% | <0.0001 | <0.0001 | |||||
Total | 1,210 | 100.00% | 5,848 | 100.00% | |||||||
Undetermined | 12 | — | 62 | — | |||||||
