Figure 5 | Scientific Reports

Figure 5

From: Frequency-specific activation of the peripheral auditory system using optoacoustic laser stimulation

Figure 5

Neural recording results. (a) Optical pulse amplitude modulation with 50 kHz LPR and 1 kHz LMR leads to 50 pulses per sinusoid period. (b) With a constant LPR of 50 kHz, the chosen paradigm leads to fewer pulses per period for higher LMR in this presented case e.g. 8 kHz. (a,b) Example of the shift of activity from 1 kHz to 8 kHz in vivo after optical stimulation at the umbo (80 mW peak power, 50 kHz LPR). The maximal activity is clearly shifting from one channel to the other in accordance to the LMR value. The optical stimulation at the round window (c) led to a similar activation pattern. The optical stimulation at the otic capsule also demonstrated the ability to achieve frequency-specific activation, however it required more energy (e.g., 120 mW) (d). The BF of each site is labeled above each set of PSTH plots. PSTHs are based on 100 trials with 1-ms time bins.

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