Figure 6 | Scientific Reports

Figure 6

From: Frequency-specific activation of the peripheral auditory system using optoacoustic laser stimulation

Figure 6

Neural recording results – pooled. (a) A linear mapping was demonstrated between the best frequency (BF) at threshold for the most activated site and the LMR in response to optical stimulation at the umbo (32 kHz LPR and 50 kHz LPR). There was strong positive correlation between the two variables LMR and BF at threshold for 32 kHz LPR (p < 0.001, r = 0.958) and 50 kHz LPR (p < 0.001, r = 0.987). (b) Comparison of the data recorded at the umbo with the two additional stimulation sites (the round window membrane and the otic capsule) at 50 kHz LPR. The correlation between the two variables LMR and BF at threshold was calculated (p < 0.001, r = 0.983 at the round window membrane and p < 0.001, r = 0.994 at the otic capsule) (n = 4). The optical threshold in peak power at the umbo is displayed for 32 kHz LPR in (c) and for 50 kHz LPR in (d). The equivalent levels for acoustic stimulation with pure tones in comparison to optical stimulation with 80 mW, using the same frequency as the LMR, is plotted for the different LMR-LPR combinations in (e). The data demonstrated mean levels between 34.6 dB SPL (10 kHz LMR, 32 kHz LPR) and 47.8 dB SPL (1 kHz LMR, 50 kHz LPR).

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