Figure 2
From: Extensive conservation of the proneuropeptide and peptide prohormone complement in mollusks
Minimum proneuropeptide/peptide prohormone complement of Mollusca. Peptide precursors were classified following criteria defined in16, distinguishing peptide families present in the last common ancestor (LCA) of eumetazoans, bilaterians, protostomians, and lophotrochozoans. Peptide families present in the LCA of Mollusca and different molluscan class-level taxa are also displayed. The differently coloured boxes correspond to the presence of a given peptide family in conchiferan (blue), aculiferan (red), and lophotrochozoan (yellow) representatives. Note that the dickkopf family proteins are not true neuropeptides or hormones, but rather secreted proteins that share a cysteine-rich domain with prokineticins.
