Table 2 Multivariate-adjusted hazard ratios (95% CIs) for incident diabetes across tertiles of CRP by gender.

From: Association of C-Reactive Protein with Risk of Developing Type 2 Diabetes Mellitus, and Role of Obesity and Hypertension: A Large Population-Based Korean Cohort Study

Gender

 

Tertiles of CRP (mg/L)

pa

T1

T2

T3

Men

Median (range)

0.35 (0.01–0.56)

0.86 (0.57–1.34)

2.40 (1.35–9.99)

 

Incident case (n)

33

43

54

 

Person-year

7196

7360

7338

 

Model1 [HR (95% CIs)]

1.0 (ref)

1.25 (0.8–1.97)

1.53 (0.99–2.36)

0.0628

Model2 [HR (95% CIs)]

1.0 (ref)

1.08 (0.67–1.74)

1.67 (1.00–2.45)

0.0272

Women

Median (range)

0.27 (0.01–0.43)

0.65 (0.44–1.01)

1.86 (1.02–9.97)

 

Incident case (n)

29

45

74

 

Person-year

12266

12350

12406

 

Model1 [HR (95% CIs)]

1.0 (ref)

1.45 (0.9–2.31)

2.29 (1.48–3.53)

<0.0001

Model2 [HR (95% CIs)]

1.0 (ref)

1.58 (0.94–2.65)

2.80 (1.73–4.52)

<0.0001

  1. Model 1: adjusted for age as continuous variable; model 2: additionally adjusted for total cholesterol concentration, resident region, smoking status, alcohol drinking, education, physical activity, family history of diabetes. P is for heterogeneity between men and women using a likelihood test = 0.3374.
  2. ap is for the linear trend using median value for each CRP tertile.
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