Figure 7 | Scientific Reports

Figure 7

From: Jujuboside A prevents sleep loss-induced disturbance of hippocampal neuronal excitability and memory impairment in young APP/PS1 mice

Figure 7

JuA induces tonic GABA current-like response. (A) Sample traces of tonic GABA current-like response in hippocampal slices from WT mice induced by aCSF and after addition of JuA (100, 150 and 300 nM) to aCSF; puff duration = 9 s, 4–6 psi. (B) Quantification of tonic GABA current amplitude shows a significant increase by JuA (aCSF, n = 12 cells; JuA 100 nM, n = 8 cells; JuA 150 nM, n = 10 cells; JuA 300 nM, n = 7 cells); error bars indicate SEM.

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