Figure 1 | Scientific Reports

Figure 1

From: p5RHH nanoparticle-mediated delivery of AXL siRNA inhibits metastasis of ovarian and uterine cancer cells in mouse xenografts

Figure 1

p5RHH nanoparticles effectively inhibit AXL and functional AXL. (A) Western blot analysis of phospho-AXL and AXL expression in ARK1 and OVCAR8 cell lines treated with vehicle, siAXL only, p5RHH-siControl, or p5RHH-siAXL. Actin is shown as a loading control. (B) qRT-PCR was performed on cells treated with p5RHH-siControl or p5RHH-siAXL and AXL mRNA expression was assessed. Data are represented as mean +/− SD and asterisks indicate significant decrease in expression compared to p5RHH-siControl as determined by the student’s t-test. ****P < 0.0001.

Back to article page