Figure 7

Effect of modified GR1SN-PBS on LPS-induced cytokine secretions. hTERT-HM cells were treated with non-modified GR1SN-PBS (“1%”), or with GR1SN-PBS modified to denature protein structures (“Heat”) or to degrade proteins (“Trypsin”), with (checkered grey bars) or without (solid grey bars) LPS stimulus (100 ng/mL). Values are presented as fold change (mean ± SEM) relative to untreated cells (white bars). Statistical significance was determined by One-way ANOVA followed by Dunnett’s post-test relative to LPS stimulus (solid black bars). *P < 0.05; **P < 0.01; ***P < 0.001 (n = 4).