Figure 2
Identification of metabolites contributing to colorectal neoplasia (CRN). Variable contributions from statistical total correlation spectroscopy (S-TOCSY) show the model coefficients for each NMR variable. (a) Healthy controls vs. all colorectal neoplasia, (b) Healthy controls vs. pre-invasive colorectal neoplasia including advance adenoma and stage 0 CRC, (c) Healthy controls vs. stage 0 CRC, and (d) Healthy controls vs. advanced adenoma. The color scale based on the value of P(coor)p, according to weight is used as a discriminator between two groups. Pp represents the modeled covariant. Signals, color coded metabolites, that significantly discriminate between the two groups were annotated on the model coefficient plot.
