Figure 3 | Scientific Reports

Figure 3

From: Urine-NMR metabolomics for screening of advanced colorectal adenoma and early stage colorectal cancer

Figure 3

ROC analysis of contributing metabolites for discrimination. (a) OPLS-DA based ROC curve analysis for diagnosis of pre-invasive colorectal neoplasia (CRN). Taurine, alanine, 3-aminoisobutyrate showed very high AUC scores. (b) Multiple ROC curve analysis for 11 metabolites contributing for discrimination. The color scale on the right shows whether each metabolite concentration level was increased or decreased in CRN. (c) ROC curves of glycerol showing high ranking on the multiple ROC curve analysis, but poor sensitivity and specificity.

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