Table 2 Dose-age dependence of 3D HepG2 spheroids after 3 -and 12 days post-seeding.

From: Effect of Spheroidal Age on Sorafenib Diffusivity and Toxicity in a 3D HepG2 Spheroid Model

Spheroidal age (days)

Mean IC50 value (µM)

SD

3

43.75

±1.34

12

168.7

±1.26