Figure 3 | Scientific Reports

Figure 3

From: Drug-loaded hyaluronic acid hydrogel as a sustained-release regimen with dual effects in early intervention of tendinopathy

Figure 3

Effect of HA hydrogel and EGCG-loaded hydrogel (10 μM EGCG) on the gene expression of TDCs (n = 4) subjected to cyclic stretching under 4% or 8% strain. Medications were added to the upper layer of the tranwell. Gene expression ratio of (A) collagen I, (B) collagen III, (C) collagen III/ collagen I, (D) Pparg (adipogenic), (E) Sox9(chondrogenic) and (F) Runx2 (osteogenic). All ratios were detected by qPCR. Data are expressed as mean ± SD (*p < 0.05) fold-changes of the expression level relative to the control (static culture). HA, HA hydrogel; HA/EGCG, EGCG-loaded hydrogel.

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