Figure 4 | Scientific Reports

Figure 4

From: Drug-loaded hyaluronic acid hydrogel as a sustained-release regimen with dual effects in early intervention of tendinopathy

Figure 4

Representative micrographs of H&E-stained Achilles tendon specimens (n = 12) 14 days after collagenase injection. (A,E) normal tendons (control group, injected with saline only), and collagenase groups injected with (B,F) saline, (C,G) HA hydrogel and (D,H) EGCG-loaded hydrogel. Arrows, rounded nucleus of tenocytes; arrowheads, focal hypercellularity; blank arrows, increased vascularity. (I) Histological evaluation scores of the H&E-stained tendon specimens 14 days after collagenase injection. Data are presented as means ± SDs (*p < 0.05). (A–D), 10 × H&E-stained; (E–H), 40 × H&E-stained from yellow box in (A–D), respectively.

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