Table 2 McArdle mice colony genotyping results between 2013 and 2018. Abbreviations.

From: Low survival rate and muscle fiber-dependent aging effects in the McArdle disease mouse model

Breedings

Post-weaning genotyping

Embryo genotyping

WT x HTZ

HTZ x HTZ

HTZ x McA

HTZ x HTZ

Offsprings

WT

HTZ

McA

WT

HTZ

McA

WT

HTZ

McA

WT

HTZ

McA

Nº mice per genotype

96

137

N.A

368

718

67

N.A

580

122

12

17

9

Genotype %

41.2

58.8

N.A

31.9

62.3

5.8

N.A

82.6

17.4

31.5

44.7

23.6

Expected Genotype %

50

50

N.A

25

50

25

N.A

50

50

25

50

25

Statistics

Fisher’s test p = 0.035

Chi-square test p < 0.001

Fisher’s test p < 0.001

Chi-square test p = 0.864

  1. N.A: Not applicable. To compare obtained versus expected mouse genotypes Fisher’s exact test (two-group comparisons, i.e., WT x HTZ and HTZ x McA breedings) and Chi-square test (three-group comparisons, i.e., HTZ x HTZ breedings) were used.
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