Table 2 Predicted regulatory genes and SNPs for the risk of gout in lymphocytes.
From: Integrative Genome-Wide Association Studies of eQTL and GWAS Data for Gout Disease Susceptibility
Gene | SNP | Proximity | Location | Result in Discovery | Result in Follow-up | ||
|---|---|---|---|---|---|---|---|
LBF | P* | LBF | P | ||||
PKD2 | 4q22.1 | 6.89 | 1.08e-05 | 6.93 | 8.98e-06 | ||
rs4148155 | cis | chr4:89273691 | 7.02 | 2.00e-05 | 7.02 | 2.00e-05 | |
NUDT9 | 4q22.1 | 6.41 | 2.87e-05 | 5.79 | 6.29e-05 | ||
rs10516801 | cis | 5.62 | 8.00e-05 | 6.02 | 8.00e-05 | ||
NAP1L5 | 4q22.1 | 5.54 | 9.52e-05 | 6.10 | 4.67e-05 | ||
rs4148155 | cis | chr4:89273691 | 5.62 | 2.00e-04 | 5.62 | 2.00e-04 | |
BRE | 2p23.2 | 5.87 | 6.11e-05 | 2.57 | 5.76e-03 | ||
rs4148155 | trans | chr4:89273691 | 2.66 | 9.90e-06 | 2.66 | 9.90e-06 | |
rs4129943 | trans | chr2:241402488 | 2.25 | 2.00e-06 | −0.102 | 2.00e-06 | |
