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Figure 1

From: Octacosanol and policosanol prevent high-fat diet-induced obesity and metabolic disorders by activating brown adipose tissue and improving liver metabolism

Figure 1

Effect of octacosanol and policosanol on body weight, body composition and fat accumulation in mice fed on chow, high fat diet (HFD) and HFD treated with octacosanol or policosanol. (a,b) Body weight (a) and body weight gain (b) of mice fed on chow, HFD and HFD treated with octacosanol or policosanol (60 mg/kg/day) for four weeks (n = 7–8). (c–e) Changes in fat mass (c), lean mass (d) and percent fat (e) measured by dual-energy X-ray absorptiometry (DEXA) analysis (n = 5). (f–h) Weight of epididymal white adipose tissue (eWAT) (f), inguinal WAT (iWAT) (g), brown adipose tissue (BAT) (h) of mice fed on chow, HFD and HFD treated with octacosanol or policosanol for four weeks (n = 7–8). Values represent mean ± standard error of mean (SEM). *P < 0.05, **P < 0.01, ***P < 0.001 by using one-way ANOVA followed by scheffe post hoc test.

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