Figure 5
From: Hox gene expression determines cell fate of adult periosteal stem/progenitor cells

Tri-lineage differentiation potential of Hox-positive and Hox-negative periosteal cells. Osteogenic (A), chondrogenic (B) and adipogenic (C) differentiation assays of frontal, parietal, hyoid, and tibia periosteal progenitors, as revealed by alizarin red, alcian blue, and oil red O staining, respectively (n = 3). Hox-negative periosteal stem/progenitor cells are almost exclusively osteogenic, while Hox-positive periosteal stem/progenitor cells exhibit tripotency. *p < 0.05, ***p < 0.001.