Figure 4

Substitution rates at the 3 codon positions, relative to the overall substitution rate, of sub-genotypes B5, C2 and C4 since 2008. Substitution rates for all three reading frames were calculated in BEAST using the relaxed exponential clock model and the GTR + G substitution model, then plotted in Tracer. Grey curves: B5; red curves: C2; blue curves: C4.