Figure 6
Polyproline II conformations are frequently populated by residues 1–40 in the disordered E7N domain. (a) The PPII region of the Ramachandran map41 is coloured in green; interestingly, almost all residues in the disordered E7N domain populate transiently this region. (b) Examples of the E7 structures populated by the extended acidic-rich region (residues 30–39). In all conformations of the RAM ensemble, the acidic-rich region is in extended conformation with two serine residues (Ser31 and Ser32) fully accessible to possible post-translational modification.
