Table 1 Patient characteristics. None of the variables were significantly different between the patient with and without sequencing data using a t-test or a Chi-squared test.

From: Whole genome sequencing identifies bacterial factors affecting transmission of multidrug-resistant tuberculosis in a high-prevalence setting

 

Cluster*

With WGS**

Age***

32.06 (17–86)

34.8 (17–86)

Female

47 (31.9%)

17 (28.3%)

Positive sputum smear

76 (51.7%)

30 (50%)

Heavy drinker in previous year

53 (36.1%)

24 (40%)

Drug use

41 (28.1%)

(Total n = 146)

20 (33.9%)

(Total n = 59)

HIV positive

3 (2.2%)

(Total n = 139)

3 (5.4%)

(Total n = 56)

Resistance Pattern# (N = 148)

N (%)

N (%)

Susceptible

26 (17.6)

9 (14.8)

  Isoniazid Resistant

18 (12.2)

13 (21.3)

  Multi-drug Resistant

56 (37.8)

31 (50.8)

  Other

36 (24.3)

8 (13.1)

  Not available

12 (8.1)

0 (0)

  1. *N = 147 unless specified (including one patient with two isolates).
  2. **N = 60 unless specified (including one patient with two isolates).
  3. ***Mean and range.
  4. #Resistance pattern for three of the sequenced strains was inferred based on mutations.
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