Figure 2 | Scientific Reports

Figure 2

From: Neural cell adhesion molecule Negr1 deficiency in mouse results in structural brain endophenotypes and behavioral deviations related to psychiatric disorders

Figure 2

Reduced number of parvalbumin (PV) positive interneurons in the hippocampus of Negr1−/− mice. Representative confocal images of the sagittal section of brains of Wt (a–d) and Negr1−/− (e–j) mice for NeuN (red), PV (green) and DAPI (blue) immunostaining. Scale bar is 250 μm for a–c, e–g and 100 μm for d and j. Graph represents mean number of NeuN positive cells (k) and PV positive cells (l) in total hippocampus, DG and in CA region. N = 3 mice for both genotype with 8–9 sections per brain. Data represent mean ± SEM, *p < 0.05, **p < 0.01, ***p < 0.001, Mann–Whitney U test.

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