Table 1 Toxicity and survival of CED of cisplatin on day 7–9 of GL261-bearing mice.
Strain | Dose | Total dose | Toxicity | Day of toxicity | Survival | ||
|---|---|---|---|---|---|---|---|
(μg/μl/h) | (μg) | (n) | (%) | (n) | (%) | ||
C57BL/6 | 0.9 | 64.8 | 2 (6) | 33.3 | 13a | 1 (4) | 25.0 |
0.1 | 7.2 | 3 (5) | 60.0 | 13–15a | 0 (2) | 0.0 | |
0.01 | 0.72 | 1 (24) | 4.16 | 14a | 9 (23) | 39.1 | |
0 (NaCl) | 0 | 0 (6) | 0.0 | — | 0 (6) | 0.0 | |
NSG | 0.01 | 0,72 | 1 (6) | 16.6 | 17a | 0 (6) | 0.0 |
0 (NaCl) | 0 | 0 (6) | 0.0 | — | 0 (6) | 0.0 | |
