Table 1 Echocardiographic parameters and heart weight (HW) to body weight (BW) ratio in RAL model treated with myocd siRNA.
Treatment Groups | LVDD (mm) | FS (%) | LVEF (%) | HW/BW ratio |
|---|---|---|---|---|
Group I (Sham Controls) | 4.34 ± 0.20 | 62.08 ± 1.18 | 78 ± 8.8 | 3.2 ± 0.5 |
Group II (Ligated) | 5.83 ± 0.38* | 34.6 ± 3.8* | 55 ± 6.7* | 4.6 ± 0.7* |
Group III (Ligated + post-myocd siRNA) | 4.95 ± 0.67# | 56.8 ± 1.97# | 72 ± 5.9# | 3.95 ± 0.3# |
Group IV (Ligated + pre-myocd siRNA) | 5.05 ± 0.45$ | 50.6 ± 2.85$ | 61 ± 7.2$ | 3.7 ± 0.4$ |
Group V (Ligated + scrambled siRNA) | 5.6 ± 0.4 | 38 ± 2.4 | 52 ± 4.4 | 4.7 ± 0.5 |
