Figure 4

Predicted probability of overall survival according to treatment assignment to 2LCTX + BSC vs. BSC alone. Survival curves were predicted from a flexible parametric survival model (log(cumulative hazard) scale) with 3 degrees of freedom for the time-invariant treatment variable and 2 degrees of freedom for the time-varying treatment variable. Abbreviations: 2LCTX – 2nd-line chemotherapy, BSC – best supportive care.