Table 1 Group allocation. 165 mice were subdivided into ten different groups. Total number of animals in each group and the injury severity score (ISS) are indicated. bsTT: bilateral soft tissue trauma; Ctrl: healthy animals without intervention; Fx: osteotomy and external fixation; HS: hemorrhagic shock; Lap: midline laparotomy; MT: multiple trauma (TxT + HS + Lap + bsTT); PT: polytrauma (PT I: TxT + HS + Fx and PT II: TxT + HS + Fx + Lap); Sham: surgical procedures without trauma; TxT: thoracic trauma.
Group | Treatment procedure | Total number [n] | ISS |
|---|---|---|---|
Control | Healthy animals without intervention | 15 | 0 |
Sham | catheter placement | 15 | 0 |
Fx | Osteotomy + external fixation | 16 | 9 |
Lap | Midline Laparotomy (2 cm) | 16 | 4 |
HS | Hemorrhagic shock + reperfusion with Ringer solution | 15 | 0 |
TxT | Thoracic trauma | 18 | 9 |
bSTT | Bilateral soft tissue trauma (lower leg) | 16 | 0 |
PT I | TxT + HS + Fx | 18 | 18 |
PT II | TxT + HS + Fx + Lap | 18 | 22 |
MT | TxT + HS + Lap + bSTT | 18 | 13 |
