Figure 6 | Scientific Reports

Figure 6

From: Functional evaluation of PDGFB-variants in idiopathic basal ganglia calcification, using patient-derived iPS cells

Figure 6

Establishment of iPS cells obtained from patients. (a) Immunocytochemical study of iPS cells for the pluripotent marker NANOG, SSEA4, and differentiation markers for three germ layers, namely, βIII-Tubulin, αSMA, and Sox17. (b) Sequencing analysis of iPS cells. PDGF-B heterozygous base substitution resulted in variant c.33_34delCT, c.160 + 2T > A, and c.457 − 1G > T. (c) G-banded karyotype analysis of iPSCs. The scale bar shows 50 μm.

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