Figure 2
From: Response kinetics reveal novel features of ageing in murine T cells
Gradual loss of proliferative capacity in Th, Tc, and Treg cells with ageing. (a) The proliferative capacity of Th, Tc, and Treg cells of young (2 months old) and aged (17–18 and 22–24 months old) mice was measured four days after exposure to a low, intermediate, or high stimulatory strength. For each condition graphs show data of one mouse that is representative of n = 6 per age group. (b) Graphs show proliferation of Th, Tc, and Treg cells by fold change of proliferation marker CellTrace in young (n = 6, 2 months old) and aged (n = 6, 22–24 months old) mice after four days cultured in the presence of a low, intermediate, or high stimulatory strength. Mean ± SEM; *p < 0.05, **p < 0.01, ***p < 0.001 for difference between young and aged mice using Two-way ANOVA.
