Figure 3 | Scientific Reports

Figure 3

From: Longitudinal monitoring of cancer cell subpopulations in monolayers, 3D spheroids, and xenografts using the photoconvertible dye DiR

Figure 3

3D tumor spheroid of ovarian cancer cells before (a) and after (b) photoconversion of the topmost peripheral region indicated by the gray box. Two regions of interest (ROI) have been selected within the image, where ROI #1 encompassed photoconverted cells while ROI #2 did not. The corresponding fluorescence spectra are shown in (c), where solid and dashed lines refer to ROIs #1 and #2, and diamonds and circles refer to before and after photoconversion, all respectively.

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