Figure 1 | Scientific Reports

Figure 1

From: Rare variants in SLC5A10 are associated with serum 1,5-anhydroglucitol (1,5-AG) in the Atherosclerosis Risk in Communities (ARIC) Study

Figure 1

Regional association plots for top hits on chromosome 17 in European ancestry sample, unconditioned and conditioned. Unconditioned analysis shows five genome-wide significant hits. Conditioning on rs61741107 results in four remaining genome-wide significant hits. Conditioning on both rs61741107 and rs148178887 results in a single genome-wide significant hit, indicating that three of the previous variants represent a single signal. Conditioning on rs61741107 and rs148178887 and rs117355297 results in no genome-wide significant hits, providing evidence that the five significant variants in this region are represented by three independent signals.

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