Figure 6
From: Metabolic stress controls mutant p53 R248Q stability in acute myeloid leukemia cells
DCA inhibits expression of macroautophagy genes via mutant p53. Different AML cell lines were treated for 24 h with different concentrations of DCA. Expression of autophagy genes (BECN1, ATG5, ATG12, LC3) was analyzed by RT-qPCR.
