Figure 2 | Scientific Reports

Figure 2

From: Structure-based Design of JOC-x, a Conjugatable Tumor Tight Junction Opener to Enhance Cancer Therapy

Figure 2

Distribution of protein multimerization states determined by SEC analysis. The SEC plots for JO-4 (left), GB3V239D (middle), and GB7V239D (right). The blue line represents the A280 absorbance for the oxidized protein while the red line represents the reduced protein. The y-axis represents the approximate fraction of each peak while the x-axis shows the elution time in minutes. The grey shaded boxes indicate the approximate retention time for (Agg) aggregates, (Multi) multimers, (T-D) trimer-dimers, (T) trimers, and (M) monomers based on MALS analysis.

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