Table 2 Number of intestinal polyps/mouse in Min mice treated with or without ITZ.

From: Novel screening system revealed that intracellular cholesterol trafficking can be a good target for colon cancer prevention

Dose (ppm)

No.

Total

Small intestine

Colon

Proximal

Middle

Distal

0

10

54.1 ± 16.5

8.4 ± 3.0

16.5 ± 5.9

29.0 ± 10.6

0.2 ± 0.4

100

10

38.5 ± 12.8*

7.4 ± 4.1

9.2 ± 4.1*

21.3 ± 6.8

0.6 ± 0.7

500

9

32.6 ± 7.5*

4.7 ± 1.7*

8.6 ± 2.6*

18.1 ± 6.8*

0.3 ± 0.5

  1. Data are presented as the means ± SD. Significantly different from the untreated control group at *p < 0.05.