Figure 6
Schematic overview of TRM cell characteristics in the renal allograft. Distribution of donor-derived and recipient-derived tissue-resident memory (TRM) cells and the phenotypic and functional characteristics of the recipient-derived TRM cells in the explanted renal allograft are depicted in a schematic overview. Cluster one and cluster two indicate TRM core genes of which the expression was measured. Cluster one consists of genes involved in T cell activation (ITGA1, IL10, and CXCR6) and cluster two consists of genes involved in T cell migration (CX3CR1, KLF2, KLF3, SELL, S1PR1).
