Table 1 Patient baseline characteristics.

From: Characterization of donor and recipient CD8+ tissue-resident memory T cells in transplant nephrectomies

 

Recipient

Transplantation

Gender

Age at nephrectomy (y)

Cause of ESRD

Number of previous renal transplants

Donor type

CMV status donor*

CMV status acceptor*

Maintenance IS

Anti-rejection treatment

Time to explantation (days)

Cause of graft failure

1.

M

30

Hypertensive nephropathy

0

L

+

Tac, MMF, Pred

MP, IvIg, plasmaferese, Alemtuzumab

8

aTCMR2B and aABMR and pyelonephritis

2.

F

48

ADPKD

0

L

+

Bela, Tac**, MMF, Pred, Basiliximab

MP, Alemtuzumab

12

aTCMR2B and aABMR

3.

M

63

Hypertension nephropathy

0

D

+

+

Tac, MMF, Pred, Basiliximab

MP, IVIg

15

aTCMR 2B and aABMR

4.

F

28

GPA

1

L

+

Tac, MMF, Pred

IVIg, Alemtuzumab

150

aTCMR3 and aABMR

5.

M

46

ADPKD

0

L

+

Tac, MMF, Pred

MP

270

aTCMR3

6.

F

67

Hypertension nephropathy

0

D

+

None#

MP

390

aTCMR3 and aABMR

7.

M

71

Diabetic nephropathy

1

D

+

+

Tac, MMF

MP

2268

aTCMR3 and

c-aABMR

8.

M

29

HUS

0

D

Tac, MMF

None

2340

c-aABMR

9.

M

24

FSGS

0

L

+

+

MMF, Pred, Ecu***

MP, IVIg

2520

c-aABMR

10.

M

51

Congenital hydronephrosis

0

D

Tac

None

3240

aTCMR2B and aABMR

11.

F

51

poststreptococcal glomerulo- nephritis

0

D

+

None#

None

3780

c-aABMR and

c-aTCMR

12.

M

53

Hypertension nephropathy

1

L

+

+

Tac, Pred

None

4320

aTCMR3

13.

M

57

Hypertension nephropathy

0

D

+

+

Aza, Pred

None

9360

End-stage kidney

  1. *CMV status prior to transplantation. **Switch from Belatacept to Tacrolimus due to rejection. ***No tacrolimus due to thrombotic microangiopathy. #Decreased IS and restarted dialysis. aABMR = acute antibody mediated rejection; ADPKD = autosomal dominant polycystic kidney disease; aTCMR = acute T cell-mediated rejection; Aza = azathioprine; CMV = cytomegalovirus; D = deceased; Ecu = eculizumab; ESRD = end-stage renal disease; FSGS = focal segmental glomerulosclerosis; GPA = granulomatosis with polyangitis; HUS = hemolytic uremic syndrome; IS = immunosuppression; IVIg = intravenous immunoglobulin; L = living; MP = methylprednisolone; MMF = mycophenolate mofetil; Pred = prednisone; Tac = tacrolimus.