Table 2 The moderation effect of the rs6265 polymorphism on the relationship between the childhood trauma questionnaire (CTQ) and the posttraumatic stress disorder checklist (PCL) score while controlling for gender, age, years of education, lifetime events checklist (LEC), hospital anxiety and depression scale (HADS), insomnia severity index (ISI), and alcohol use disorders identification test (AUDIT).
Variables | B | S.E. | t | R 2 |
|---|---|---|---|---|
Model 1 | ||||
(Constant) | −30.525 | 10.331 | −2.955** | 0.355*** |
gender | −4.329 | 2.336 | −1.854 |  |
age | −0.203 | 0.085 | −2.408* |  |
years of education | −1.212 | 0.359 | −3.376** |  |
LEC | 2.353 | 0.512 | −3.376*** |  |
rs6265 | 12.375 | 6.553 | 1.888 | Â |
CTQ | 0.480 | 0.109 | 4.384*** | Â |
rs6265 × CTQ | −0.326 | 0.128 | −2.548* |  |
rs6265 | Effect | Boot S.E . | Boot Confidence Interval | |
CC (Val/Val) | 0.480*** | 0.109 | [0.264, 0.695] | |
CT & TT (Met allele) | 0.154 | 0.085 | [−0.013, 0.321] | |
Model 2 | ||||
(Constant) | −8.607 | 7.073 | −1.217 | 0.757*** |
gender | 0.949 | 1.659 | 0.572 | Â |
age | −0.098 | 0.055 | −1.781 |  |
years of education | −0.220 | 0.231 | −0.952 |  |
LEC | 0.882 | 0.331 | 2.662** | Â |
HADS - anxiety | 1.487 | 0.234 | 6.361*** | Â |
HADS - depression | 1.030 | 0.242 | 4.257*** | Â |
ISI | 0.612 | 0.122 | 5.028*** | Â |
AUDIT | −0.284 | 0.218 | −1.304 |  |
rs6265 | 7.690 | 4.107 | 1.872 | Â |
CTQ | 0.236 | 0.070 | 3.375** | Â |
rs6265 × CTQ | −0.161 | 0.081 | −1.988* |  |
rs6265 | Effect | Boot S.E . | Boot Confidence Interval | |
CC (Val/Val) | 0.236*** | 0.700 | [0.098, 0.374] | |
CT & TT (Met allele) | 0.076 | 0.053 | [−0.029, 0.180] | |