Figure 2

Identification of genes sensitive to patient- versus PDX-RNAseq bioinformatics pipelines. Nine patient donor tumors were processed through patient- and PDX-RNAseq piplines separately; differential expressed genes (DEGs) between the two pipelines are used to determine genes sensitive to pipeline differences. (a) MA (M: log ratio, A: Mean average) plot with DEGs highlighted in red; (b) Distribution of phast conservation score for all genes and DEGs caused by pipeline differences.