Figure 5

Hepatic protein levels of (A) ARNTL, (B) REV-ERBα, and (C) NFIL3 in male C57BL/6 mice orally gavaged with sesame oil vehicle or 30 µg/kg TCDD every 4 days for 28 days. Data points represent the average of 3 individual mice ± standard error of the mean measured using capillary electrophoresis (WES ProteinSimple System). Statistical significance (*p ≤ 0.05) between vehicle and TCDD was determined using a two-way ANOVA analysis followed by Sidak’s multiple comparison test. Diurnal rhythmicity was assessed using JTK_CYCLE (# BH q ≤ 0.1). Data are double-plotted along the x-axis for better visualization of rhythmicity.