Table 1 RefGenes of differentially methylated regions (DMRs) with greatest difference in the averaged β-values.
GENE-SYMBOL | AVE_Beta of normal group | AVE_Beta of obese group | Delta | RefSeq_ACCESSION | ENTREZ_GENEID | TYPE_OF_GENE | DESCRIPTION |
|---|---|---|---|---|---|---|---|
LCLAT1 | 0.4609843 | 0.0145585 | −0.526158 | NM_001304445 | 253558 | protein-coding | lysocardiolipin acyltransferase 1 |
CCL3L3 | 0.6155401 | 0.3475144 | −0.25072 | NM_001001437 | 414062 | protein-coding | C-C motif chemokine ligand 3 like 3 |
LOC101929384 | 0.289783 | 0.09906 | −0.23547 | NR_120475 | 101929384 | ncRNA | uncharacterized LOC101929384 |
KIRREL3-AS2 | 0.2568615 | 0.0921788 | −0.208665 | NR_046986 | 100874251 | ncRNA | KIRREL3 antisense RNA 2 |
CTPS1 | 0.6850519 | 0.87511 | 0.202434 | NM_001301237 | 1503 | protein-coding | CTP synthase 1 |
OR2L13 | 0.3626859 | 0.5284353 | 0.1977 | NM_175911 | 284521 | protein-coding | olfactory receptor family 2 subfamily L member 13 |
IL20 | 0.3886124 | 0.1850412 | −0.197166 | NM_018724 | 50604 | protein-coding | interleukin 20 |
PPP1R2 | 0.2695188 | 0.4360325 | 0.156859 | NM_001291505 | 5504 | protein-coding | protein phosphatase 1 regulatory inhibitor subunit 2 |
ST3GAL6 | 0.213688 | 0.0722118 | −0.14837 | NM_001271142 | 10402 | protein-coding | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
ZSCAN31 | 0.24028 | 0.0924391 | −0.132292 | NM_001243244 | 64288 | protein-coding | zinc finger and SCAN domain containing 31 |
LINC00377 | 0.2347052 | 0.0984455 | −0.129794 | NR_125770 | 103724386 | ncRNA | long intergenic non-protein coding RNA 377 |
PTPRQ | 0.2012982 | 0.0693708 | −0.129505 | NM_001145026 | 374462 | protein-coding | protein tyrosine phosphatase, receptor type Q |
LOC339166 | 0.1262455 | 0.0104135 | −0.125039 | NR_040000 | 339166 | ncRNA | uncharacterized LOC339166 |
CCDC68 | 0.1115733 | 0.0209919 | −0.122825 | NM_025214 | 80323 | protein-coding | coiled-coil domain containing 68 |
MARVELD2 | 0.2159227 | 0.0842055 | −0.118099 | NM_001038603 | 153562 | protein-coding | MARVEL domain containing 2 |
BMP4 | 0.23403 | 0.1188948 | −0.11401 | NM_001202 | 652 | protein-coding | bone morphogenetic protein 4 |
FBXO44 | 0.211308 | 0.091532 | −0.111535 | NM_183412 | 93611 | protein-coding | F-box protein 44 |
BRCA2 | 0.156211 | 0.2569725 | 0.103704 | NM_000059 | 675 | protein-coding | breast cancer 2 |
CHST10 | 0.1315424 | 0.0611276 | −0.09368 | NM_004854 | 9486 | protein-coding | carbohydrate sulfotransferase 10 |
ANXA11 | 0.2397733 | 0.1431341 | −0.090493 | NM_001278407 | 311 | protein-coding | annexin A11 |
CD40 | 0.086086 | 0.1608967 | 0.08881 | NM_001250 | 958 | protein-coding | CD40 molecule |
ARHGAP39 | 0.1064887 | 0.0375751 | −0.078823 | NM_001308208 | 80728 | protein-coding | Rho GTPase activating protein 39 |
LGSN | 0.1821024 | 0.061384 | −0.077074 | NM_016571 | 51557 | protein-coding | lengsin, lens protein with glutamine synthetase domain |
FBXO44 | 0.1132692 | 0.0343917 | −0.076007 | NM_001304791 | 93611 | protein-coding | F-box protein 44 |
CECR1 | 0.1888989 | 0.1022042 | −0.074676 | NM_177405 | 51816 | protein-coding | cat eye syndrome chromosome region, candidate 1 |
SLC6A13 | 0.1002082 | 0.0445989 | −0.069311 | NM_001190997 | 6540 | protein-coding | solute carrier family 6 member 13 |
YBX2 | 0.102823 | 0.0424958 | −0.060535 | NM_015982 | 51087 | protein-coding | Y-box binding protein 2 |
RPP14 | 0.0891559 | 0.1503356 | 0.056264 | NR_049755 | 11102 | protein-coding | ribonuclease P/MRP 14kDa subunit |
FBXO44 | 0.1109388 | 0.0407703 | −0.054111 | NM_183413 | 93611 | protein-coding | F-box protein 44 |
UBE4A | 0.0837289 | 0.1201833 | 0.052674 | NM_004788 | 9354 | protein-coding | ubiquitination factor E4A |
