Figure 6

Correlation between the binding energies and the experimental KD values. The binding scores are averaged in the five independent runs (<Ebind>5runs; <EbindRSA >5runs for the RSA-corrected values) and compared to the logarithm of KD values (lnKD). The CRM1-binders with KD values are shown in filled markers with error bars which are the standard deviation during the five runs. The false positives are shown in orange empty markers. In the middle, the correlation between R2 and the weights for RSA during the Ebind correction is shown. The weight of 0.35 were applied for calculation of EbindRSA.