Figure 3
CPT treatment does not influence the viral entry steps of the oncolytic MV. (A) Schematic representations of synchronized infection analysis on early viral entry. (B) CPT’s effect on free MV particles. (C) CPT’s effect on MV attachment. (D) CPT’s effect on MV entry/fusion. For all experiments, final MV MOI was 0.1, DMSO (0.1%) was included as negative control, and PUG = 50 µM was included as positive control treatment in each condition. All data shown are means ± SEM (*P < 0.05 compared to Virus Only treatment) from three independent experiments.
