Figure 5 | Scientific Reports

Figure 5

From: Accurate early prediction of tumour response to PDT using optical coherence angiography

Figure 5

Histological assessment of treatment outcomes at t = 7 days post PDT. Left column’s two panels exhibit an illustrative responder. (a) Total tumour necrosis (>95%) in the central part of tumour (blue arrows). (b) Total necrosis of ‘normal’ ear tissue ~2 mm distant from the tumour edge (but still within the PDT treatment field). Right column’s two panels exhibit an illustrative non-responder. (c) Partial tumour necrosis (~75%) and viable tumour region. (d) Undamaged ‘normal’ ear tissue ~2 mm away from the tumour edge (but still within the PDT treatment field). Central white-light photograph shows the colour-coded orientation of the two histological sections displayed for each illustrative case.

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