Table 4 Glaucoma Symptom Scale (GSS) and 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) scores by visit.

From: Vision-related quality of life and symptom perception change over time in newly-diagnosed primary open angle glaucoma patients

Score

Baseline N = 178 Mean (SD)

6-month N = 178 Mean (SD)

12-month N = 178 Mean (SD)

Mixed modelsa

Slopes/OR (for 6-month increase) [CI]

P-value

Glaucoma Symptoms Scale

Symp-6

76.2 (21.1)

77.0 (19.6)

79.8 (19.9)

1.81 [0.55; 3.08]

<0.01*

Func-4

81.2 (20.1)

81.3 (20.8)

85.8 (18.2)

2.32 [0.99; 3.64]

<0.01*

Total Score

78.1 (18.0)

78.7 (17.6)

82.2 (17.5)

2.06 [1.03; 3.10]

<0.01*

National Eye Institute Visual Function Questionnaire (NEI-VFQ-25)

General health

60.4 (17.0)

62.3 (17.9)

64.6 (19.4)

2.13 [0.99; 3.28]

<0.01*

General vision

65.8 (15.4)

67.4 (15.0)

69.8 (15.7)

2.01 [0.89; 3.13]

<0.01*

Ocular pain

79.5 (19.9)

81.3 (17.6)

83.3 (18.5)

1.90 [0.57; 3.22]

<0.01*

Near activities

86.2 (17.4)

87.8 (15.8)

89.8 (14.7)

1.80 [0.69; 2.91]

<0.01*

Distance activitiesb–n (%) (100)

92 (51.7)

93 (52.3)

98 (55.1)

1.24 [0.80; 1.91]

0.33

Social functioningb–n (%) (100)

155 (87.1)

147 (82.6)

154 (86.5)

0.96 [0.63; 1.45]

0.83

Mental health

83.8 (18.2)

82.7 (18.8)

86.0 (17.4)

1.14 [0.15; 2.14]

0.03*

Role difficultiesb–n (%) (100)

123 (69.1)

121 (68.0)

137 (77.0)

1.80 [1.06; 3.06]

0.03*

Dependencyb – n (%) (100)

144 (80.9)

142 (79.8)

152 (85.4)

1.58 [0.85; 2.94]

0.15

Drivingc

87.8 (16.4)

88.5 (16.2)

90.6 (14.8)

0.99 [0.03; 1.94]

0.04*

Color visionb–n (%) (100)

168 (94.4)

166 (93.3)

163 (91.6)

0.93 [0.29; 2.94]

0.90

Peripheral visionb–n (%) (100)

140 (78.7)

130 (73.0)

139 (78.1)

1.32 [0.71; 2.48]

0.38

Total Score

88.3 (11.3)

88.6 (10.7)

90.0 (11.2)

0.87 [0.32; 1.41]

<0.01*

  1. Legend: N: Number of participants; OR: Odds Ratio; CI: Confidence Interval; aLongitudinal linear mixed model or logistic longitudinal mixed model (modeled the probability of score =ā€‰ā€œ100ā€); bDichotomous score (ā€˜ā€‰= 100’, ā€˜<100’); cData available for 145 patients. *Significant values.