Figure 2
From: miR-150-5p represses TP53 tumor suppressor gene to promote proliferation of colon adenocarcinoma
Expression of miR-150-5p and TP53 in colon cancer specimens and cell lines. The expression levels of miR-150-5p (A) or TP53 protein (B) or TP53 mRNA (C) were determined in both colon adenocarcinoma (tumor) and non-cancerous (normal) adjacent tissues. (D) Representative images of immunofluorescence staining, using antibodies against TP53 or COX-2, on isolated cancer cells purified from 3 select specimens. (E) Expression levels of miR-150-5p and TP53 mRNA, as determined by RT-qPCR, in colon adenocarcinoma cell lines (N = 3) and the normal human colon epithelial cell line CCD 841 CoN. *P < 0.01.
