Table 1 Patients’ characteristics according to two age groups and log NT-proBNP tertile

From: Characterisation of N-terminal pro-brain natriuretic peptide in dialysis patients and its reduced prognostic significance in the elderly

Tertile of Log NT-proBNP

Group-Y (age < 75)

Group-O (age ≧ 75)

Tertile 1

Tertile 2

Tertile 3

p-value

Tertile 1

Tertile 2

Tertile 3

p-value

Number

204

203

204

 

103

103

103

 

NT-proBNP, pg/mL

1385 (570–2127)

3650 (2337–5536)

11953 (6247–86425)

<0.01

2690 (852–4042)

6080 (4274–10124)

24100 (11311–130400)

<0.01

Log NT-proBNP, pg/mL

3.10 (0.18)

3.56 (0.12)

4.17 (0.34)

<0.01

3.38 (0.21)

3.80 (0.12)

4.42 (0.31)

<0.01

Age, years

58.2 (10.3)

62.4 (8.9)

62.5 (8.5)

<0.01

80.3 (4.6)

81.4 (4.9)

82.1 (5.8)

0.04

Sex, women, %

36.3%

48.8%

37.3%

0.02

37.9%

51.5%

57.3%

0.02

Dry weight, kg

Women

51.9 (10.4)

48.1 (8.2)

46.3 (9.5)

<0.01

44.8 (9.1)

44.6 (7.3)

41.3 (7.7)

0.04

Men

62.0 (10.6)

58.9 (10.1)

57.3 (9.8)

<0.01

55.3 (8.1)

53.6 (7.5)

50.2 (6.1)

<0.01

Standard score of dry weight

54.8 (10.6)

51.4 (9.3)

49.7 (9.8)

<0.01

47.9 (8.6)

46.9 (7.6)

43.6 (7.3)

<0.01

Log dialysis vintage, months

1.90 (0.38)

2.01 (0.35)

1.99 (0.33)

0.01

1.71 (0.33)

1.87 (0.33)

1.88 (0.32)

<0.01

Cardiothoracic ratio, %

48.1 (4.2)

50.2 (4.1)

53.3 (5.5)

<0.01

51.1 (4.8)

52.8 (4.1)

55.8 (5.4)

<0.01

Basal kidney disease, diabetes, %

19.6%

18.7%

35.3%

<0.01

21.4%

17.5%

22.3%

0.66

Inter-dialytic body weight gain, %

4.17 (1.55)

4.76 (1.57)

5.11 (2.19)

<0.01

4.34 (1.67)

4.70 (1.70)

4.58 (2.15)

0.40

CVD history, %

21.6%

23.2%

38.2%

<0.01

31.1%

37.9%

51.5%

0.01

Current smoking status, %

17.6%

15.3%

22.1%

0.20

8.7%

7.8%

6.8%

0.87

Predialysis SBP, mmHg

149 (19)

157 (18)

160 (19)

<0.01

155 (16)

155 (18)

156 (19)

0.94

Antihypertensive drug use, %

68.6%

78.3%

83.8%

<0.01

73.8%

78.6%

77.7%

0.68

Albumin, g/dL

4.06 (0.40)

3.97 (0.41)

3.87 (0.54)

<0.01

3.68 (0.36)

3.62 (0.43)

3.52 (0.45)

0.02

Log C-reactive protein, mg/dL

−0.95 (0.52)

−0.97 (0.50)

−0.73 (0.64)

<0.01

−0.80 (0.54)

−0.77 (0.59)

−0.59 (0.58)

0.02

Non-HDL cholesterol, mg/dL

115 (29)

116 (33)

109 (33)

0.03

115 (27)

111 (31)

109 (30)

0.28

  1. CVD, cardiovascular disease; HDL, high-density lipoprotein; NT-proBNP, N-terminal pro-brain natriuretic peptide; SBP, systolic blood pressure.
  2. NT-proBNP, median (25–75 percentile).
  3. The per cent of the inter-dialytic body weight gain was calculated as mean 3-consecutive inter-dialytic body weight gain (kg) comparable to dry weight (kg).
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