Table 2 Risks of tertiles log NT-proBNP for mortalities up to 7-year follow-up.

From: Characterisation of N-terminal pro-brain natriuretic peptide in dialysis patients and its reduced prognostic significance in the elderly

 

All-cause death

Non-malignancy-related death

CVD-related death

HR (95% CI)

p-value

HR (95% CI)

p-value

HR (95% CI)

p-value

Unadjusted

Total cohort

T1

ref

 

ref

 

ref

 

T2

2.35 (1.66 to 3.34)

<0.01

2.51 (1.72 to 3.67)

<0.01

2.68 (1.52 to 4.72)

<0.01

T3

5.08 (3.67 to 7.03)

<0.01

5.61 (3.94 to 7.99)

<0.01

6.06 (3.56 to 10.31)

<0.01

Group-Y

T1

ref

 

ref

 

ref

 

T2

2.60 (1.40 to 4.85)

<0.01

3.33 (1.57 to 7.06)

<0.01

2.84 (1.11 to 7.27)

0.03

T3

6.99 (3.95 to 12.36)

<0.01

9.71 (4.84 to 19.45)

<0.01

8.37 (3.55 to 19.74)

<0.01

Group-O

T1

ref

 

ref

 

ref

 

T2

1.21 (0.83 to 1.76)

0.32

1.24 (0.83 to 1.84)

0.29

1.71 (0.90 to 3.24)

0.1

T3

2.17 (1.52 to 3.09)

<0.01

2.38 (1.64 to 3.44)

<0.01

2.65 (1.42 to 4.96)

<0.01

Adjusted

Total cohort

T1

ref

 

ref

 

ref

 

T2

1.49 (1.01 to 2.20)

0.04

1.50 (0.99 to 2.26)

0.06

1.73 (0.93 to 3.19)

0.08

T3

2.36 (1.59 to 3.51)

<0.01

2.35 (1.54 to 3.59)

<0.01

2.93 (1.57 to 5.46)

<0.01

Group-Y

T1

ref

 

ref

 

ref

 

T2

1.70 (0.89 to 3.25)

0.11

2.07 (0.95 to 4.51)

0.07

1.91 (0.72 to 5.06)

0.20

T3

2.95 (1.54 to 5.67)

<0.01

3.78 (1.74 to 8.22)

<0.01

3.66 (1.39 to 9.65)

0.01

Group-O

T1

ref

 

ref

 

ref

 

T2

1.00 (0.64 to 1.58)

1.00

0.98 (0.61 to 1.55)

0.92

1.51 (0.72 to 3.16)

0.27

T3

1.50 (0.94 to 2.40)

0.09

1.49 (0.92 to 2.41)

0.10

1.88 (0.85 to 4.17)

0.12

  1. Adjusted model. Adjusted with age (+1 SD), DW standard score (+1 SD), sex, Alb (+1 SD), log CRP, CVD history, SBP (+1 SD), CTR (+1 SD), non-HDL-c (+1 SD), log dialysis vintage, current smoking, inter-dialytic body weight gain comparable to dry weight (+1%), basal kidney disease (diabetes), and antihypertensive medicine use.