Figure 3
Behavioural responses of WT and Trpv4 KO mice to sour tastants. (a) Two-bottle tests were used to evaluate behavioural responses to sweet (sucrose, 30 mM), umami (monosodium glutamate, 100 mM), bitter (denatonium benzoate, 1 mM), salty (sodium chloride, 300 mM), and sour taste (citric acid, 10 mM) stimuli. Data presented as the means ± SEM for 8 mice. For statistical analysis, Student’s t-test was used. *P < 0.05 vs. WT. (b) Two-bottle (left) and brief-access (right) tests were used to measure behavioural responses to sour taste stimuli. Data presented as the means ± SEM for 8 mice. For statistical analysis, two-way ANOVA followed by Bonferroni’s multiple comparison test was used. *P < 0.05 vs. WT.
